MULTHAUP, Gerd: search on Z-Library

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1

A modified β-amyloid hypothesis: intraneuronal accumulation of the β-amyloid peptide – the first step of a fatal cascade

Oliver Wirths, Gerd Multhaup, Thomas A. Bayer

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 150 KB

english, 2004

2

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Kang, Jie, Lemaire, Hans-Georg, Unterbeck, Axel, Salbaum, J. Michael, Masters, Colin L., Grzeschik, Karl-Heinz, Multhaup, Gerd, Beyreuther, Konrad, Müller-Hill, Benno

Journal:

Year:

1987

File:

PDF, 466 KB

1987

3

Copper Transport Mediated by Nanocarrier Systems in a Blood–Brain Barrier In Vitro Model

Fehse, Susanne, Nowag, Sabrina, Quadir, Mohiuddin, Kim, Kwang Sik, Haag, Rainer, Multhaup, Gerd

Journal:

Biomacromolecules

Year:

2014

Language:

english

File:

PDF, 3.99 MB

english, 2014

4

Environmental Copper and Manganese in the Pathophysiology of Neurologic Diseases (Alzheimer's Disease and Manganism)

Hermann H. Dieter, Thomas A. Bayer, Gerd Multhaup

Journal:

CLEAN – Soil, Air, Water

Year:

2005

File:

PDF, 66 KB

2005

5

Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein

Anna Henry, Qiao-Xin LI, Denise Galatis, Lars Hesse, Gerd Multhaup, Konrad Beyreuther, Colin L. Masters, Roberto Cappai

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 1.35 MB

english, 1998

6

Proteolytic Fragments of Alzheimer’s Disease-Associated Presenilin 1 Are Present in Synaptic Organelles and Growth Cone Membranes of Rat Brain

Dirk Beher, Christine Elle, John Underwood, John B. Davis, Robin Ward, Eric Karran, Colin L. Masters, Konrad Beyreuther, Gerd Multhaup

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 284 KB

english, 1999

7

Specific binding of the alzheimer βA4 amyloid precursor to collagen, laminin, and heparin

Gerd Multhaup, Ashley I. Bush, Peter Pollwein, Colin L. Masters, Konrad Beyreuther

Journal:

The Protein Journal

Year:

1992

Language:

english

File:

PDF, 239 KB

english, 1992

8

Copper and clioquinol treatment in young APP transgenic and wild-type mice: effects on life expectancy, body weight, and metal-ion levels

Stephanie Schäfer, Frank-Gerald Pajonk, Gerd Multhaup, Thomas A. Bayer

Journal:

Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 338 KB

english, 2007

9

Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease

Oliver Wirths, Joachim Weis, Jacek Szczygielski, Gerd Multhaup, Thomas A. Bayer

Journal:

Acta Neuropathologica

Year:

2006

Language:

english

File:

PDF, 1006 KB

english, 2006

10

Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer’s disease

Thomas A. Bayer, Krzysztof Paliga, Sascha Weggen, O. D. Wiestler, Konrad Beyreuther, Gerd Multhaup

Journal:

Acta Neuropathologica

Year:

1997

Language:

english

File:

PDF, 399 KB

english, 1997

11

Reverse relationship between β-amyloid precursor protein and β-amyloid peptide plaques in Down’s syndrome versus sporadic/familial Alzheimer’s disease

Rupert Egensperger, Sascha Weggen, Nobua Ida, Gerd Multhaup, Ralf Schnabel, Konrad Beyreuther, T. A. Bayer

Journal:

Acta Neuropathologica

Year:

1999

Language:

english

File:

PDF, 260 KB

english, 1999

12

Intake of copper has no effect on cognition in patients with mild Alzheimer’s disease: a pilot phase 2 clinical trial

Holger Kessler, Thomas A. Bayer, Daniela Bach, Thomas Schneider-Axmann, Tillmann Supprian, Wolfgang Herrmann, Manfred Haber, Gerd Multhaup, Peter Falkai, Frank-Gerald Pajonk

Journal:

Journal of Neural Transmission

Year:

2008

Language:

english

File:

PDF, 246 KB

english, 2008

13

Effect of copper intake on CSF parameters in patients with mild Alzheimer’s disease: a pilot phase

Holger Kessler, Frank-Gerald Pajonk, Daniela Bach, Thomas Schneider-Axmann, Peter Falkai, Wolfgang Herrmann, Gerd Multhaup, Jens Wiltfang, Stephanie Schäfer, Oliver Wirths, Thomas A. Bayer

Journal:

Journal of Neural Transmission

Year:

2008

Language:

english

File:

PDF, 217 KB

english, 2008

14

Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

Oliver Wirths, Tobias Bethge, Andrea Marcello, Anja Harmeier, Sadim Jawhar, Paul J. Lucassen, Gerd Multhaup, David L. Brody, Thomas Esparza, Martin Ingelsson, Hannu Kalimo, Lars Lannfelt, Thomas A. Ba

Journal:

Journal of Neural Transmission

Year:

2010

Language:

english

File:

PDF, 694 KB

english, 2010

15

Interaction kinetics of the copper-responsive CopY repressor with thecoppromoter ofEnterococcus hirae

Reto Portmann, David Magnani, JivkoV. Stoyanov, Ariane Schmechel, Gerd Multhaup, Marc Solioz

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2004

Language:

english

File:

PDF, 1.58 MB

english, 2004

16

Real-time kinetics of discontinuous and highly conformational metal-ion binding sites of prion protein

Carina Treiber, Andrew R. Thompsett, Rüdiger Pipkorn, David R. Brown, Gerd Multhaup

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2007

Language:

english

File:

PDF, 373 KB

english, 2007

17

Detection of prion epitopes on PrPc and PrPsc of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP

Yuan, Fang F, Biffin, Sandra, Brazier, Marcus W, Suarez, Monica, Cappai, Roberto, Hill, Andrew F, Collins, Steven J, Sullivan, John S, Middleton, Deborah, Multhaup, Gerd, Geczy, Andrew F, Masters, Col

Journal:

Immunology & Cell Biology

Year:

2005

Language:

english

File:

PDF, 699 KB

english, 2005

18

Human Brain βA4 Amyloid Protein Precursor of Alzheimer's Disease: Purification and Partial Characterization

Robert D. Moir, Ralph N. Martins, Ashley I. Bush, David H. Small, Elizabeth A. Milward, Baden A. Rumble, Gerd Multhaup, Konrad Beyreuther, Colin L. Masters

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 1.13 MB

english, 1992

19

Copper is required for prion protein-associated superoxide dismutase-l activity in Pichia pastoris

Carina Treiber, Rüdiger Pipkorn, Christoph Weise, Gudrun Holland, Gerd Multhaup

Journal:

Year:

2007

Language:

english

File:

PDF, 246 KB

english, 2007

20

Intraneuronal APP/Aβ Trafficking and Plaque Formation in β-Amyloid Precursor Protein and Presenilin-1 Transgenic Mice

Oliver Wirths, Gerd Multhaup, Christian Czech, Nicole Feldmann, Véronique Blanchard, Günter Tremp, Konrad Beyreuther, Laurent Pradier, Thomas A. Bayer

Journal:

Brain Pathology

Year:

2002

Language:

english

File:

PDF, 737 KB

english, 2002

21

Key Factors in Alzheimer's Disease: β-amyloid Precursor Protein Processing, Metabolism and Intraneuronal Transport

Thomas A. Bayer, Oliver Wirths, Katalin Majtényi, Tobias Hartmann, Gerd Multhaup, Konrad Beyreuther, Christian Czech

Journal:

Brain Pathology

Year:

2001

Language:

english

File:

PDF, 236 KB

english, 2001

22

Fibrils from brains of cows with new cattle disease contain scrapie-associated protein

Hope, James, Reekie, Laura J. D., Hunter, Nora, Multhaup, Gerd, Beyreuther, Konrad, White, Heather, Scott, Anthony C., Stack, Michael J., Dawson, Michael, Wells, Gerald A. H.

Journal:

Year:

1988

File:

PDF, 424 KB

1988

23

10.1038/7562

Parker, Michael W., Rossjohn, Jamie, Cappai, Roberto, Feil, Susanne C., Henry, Anna, McKinstry, William J., Galatis, Denise, Hesse, Lars, Multhaup, Gerd, Beyreuther, Konrad, Masters, Colin L.

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 1.20 MB

english, 1999

24

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42

Munter, Lisa-Marie, Voigt, Philipp, Harmeier, Anja, Kaden, Daniela, Gottschalk, Kay E, Weise, Christoph, Pipkorn, Rüdiger, Schaefer, Michael, Langosch, Dieter, Multhaup, Gerd

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 322 KB

english, 2007

25

The amyloid precursor protein and its homologues: Structural and functional aspects of native and pathogenic oligomerization

Daniela Kaden, Lisa Marie Munter, Bernd Reif, Gerd Multhaup

Journal:

European Journal of Cell Biology

Year:

2012

Language:

english

File:

PDF, 477 KB

english, 2012

26

Diverse fibrillar peptides directly bind the Alzheimer’s amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation

Anthony R White, Fran Maher, Marcus W Brazier, Michael F Jobling, James Thyer, Leanne R Stewart, Andrew Thompson, Riki Gibson, Colin L Masters, Gerd Multhaup, Konrad Beyreuther, Colin J Barrow, Steven

Journal:

Year:

2003

Language:

english

File:

PDF, 1009 KB

english, 2003

27

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Anthony R White, Rosario Reyes, Julian F.B Mercer, James Camakaris, Hui Zheng, Ashley I Bush, Gerd Multhaup, Konrad Beyreuther, Colin L Masters, Roberto Cappai

Journal:

Year:

1999

Language:

english

File:

PDF, 128 KB

english, 1999

28

Possible mechanisms of APP-mediated oxidative stress in Alzheimer’s disease

Gerd Multhaup, Stefan Scheuermann, Andrea Schlicksupp, Andreas Simons, Markus Strauss, André Kemmling, Christian Oehler, Roberto Cappai, Rüdiger Pipkorn, Thomas A Bayer

Journal:

Free Radical Biology and Medicine

Year:

2002

Language:

english

File:

PDF, 170 KB

english, 2002

29

Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie

James HOPE, Gerd MULTHAUP, Laura J. D. REEKIE, Richard H. KIMBERLIN, Konrad BEYREUTHER

Journal:

Year:

1988

Language:

english

File:

PDF, 1.07 MB

english, 1988

30

Human Amyloid Precursor-Like Protein 1 : cDNA Cloning, Ectopic Expression in COS-7 Cells and Identification of Soluble Forms in the Cerebrospinal Fluid

Krzysztof Paliga, Gisela Peraus, Sylvia Kreger, Ulrike Dürrwang, Lars Hesse, Gerd Multhaup, Colin L. Masters, Konrad Beyreuther, Andreas Weidemann

Journal:

Year:

1997

Language:

english

File:

PDF, 3.30 MB

english, 1997

31

Interaction of the CopZ Copper Chaperone with the CopA Copper ATPase of Enterococcus hirae Assessed by Surface Plasmon Resonance

Gerd Multhaup, Daniel Strausak, Karl-Dimiter Bissig, Marc Solioz

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 83 KB

english, 2001

32

Chelation and Intercalation: Complementary Properties in a Compound for the Treatment of Alzheimer's Disease

Robert A. Cherny, Kevin J. Barnham, Toni Lynch, Irene Volitakis, Qiao-Xin Li, Catriona A. McLean, Gerd Multhaup, Konrad Beyreuther, Rudolph E. Tanzi, Colin L. Masters, Ashley I. Bush

Journal:

Journal of Structural Biology

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

33

Localization of Alzheimer βA4 amyloid precursor protein at central and peripheral synaptic sites

Walter Schubert, Reinhard Prior, Andreas Weidemann, Heinrich Dircksen, Gerd Multhaup, Colin L. Masters, Konrad Beyreuther

Journal:

Year:

1991

Language:

english

File:

PDF, 1.38 MB

english, 1991

34

The βA4 amyloid precursor protein binding to copper

Lars Hesse, Dirk Beher, Colin L. Masters, Gerd Multhaup

Journal:

Year:

1994

Language:

english

File:

PDF, 743 KB

english, 1994

35

Interaction between the zinc(II) and the heparin binding site of the Alzheimer's disease βA4 amyloid precursor protein (APP)

Gerd Multhaup, Ashley I. Bush, Peter Pollwein, Colin L. Masters

Journal:

Year:

1994

Language:

english

File:

PDF, 325 KB

english, 1994

36

Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain

Sven O. Dahms, Ina Könnig, Dirk Roeser, Karl-Heinz Gührs, Magnus C. Mayer, Daniela Kaden, Gerd Multhaup, Manuel E. Than

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 2.12 MB

english, 2012

37

Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

Christoph Schmitz, Bart P.F. Rutten, Andrea Pielen, Stephanie Schäfer, Oliver Wirths, Günter Tremp, Christian Czech, Veronique Blanchard, Gerd Multhaup, Payam Rezaie, Hubert Korr, Harry W.M. Steinbusc

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 1.46 MB

english, 2004

38

A novel substrate for analyzing Alzheimer’s disease γ-secretase

Stefan F. Lichtenthaler, Gerd Multhaup, Colin L. Masters, Konrad Beyreuther

Journal:

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

39

Separation of presenilin function in amyloid β-peptide generation and endoproteolysis of Notch

Christian Haass, Luka Kulic, Anja Capell, Harold Steiner, Gerd Multhaup, David Teplow, Helmut Romig

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 177 KB

english, 2000

40

The structure and function of the amyloid precursor protein N-terminal region

Roberto Cappai, Anthony R. White, Gerd Multhaup, Kevin Barnham, William J. McKinstry, Elise Needham, Denise Galatis, Jamie Rossjohn

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 205 KB

english, 2000

41

O3-04-06 Structural and functional analysis of the Alzheimer's disease amyloid precursor protein copper binding domain

Roberto Cappai, Geoffrey Kong, William McKinstry, Denise Galatis, Julian Adams, Shane Bellingham, James Camakaris, Cyril Curtain, Nicholas Williamson, Anthony White, Konrad Beyreuther, Gerd Multhaup,

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

42

P1-211 Characterization of Aβ-dimerization in an in vivo transmembrane dimerization selection system

Lisa M. Munter, Eric Lindner, Dieter Langosch, Gerd Multhaup

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

43

789 Exon 15 of APP regulates βA4 production and polarized secretion of APP

Tobias Hartmann, Christian Bergsdorf, Sophie Bieger, Pentti J. Tienari, Nobuo Ida, Gerd Multhaup, Rupert Sandbrink, Andreas Weidemann, Colin L. Masters, Konrad Beyreuther

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 143 KB

english, 1996

44

Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

Oliver Wirths, Gerd Multhaup, Christian Czech, Véronique Blanchard, Saliha Moussaoui, Günter Tremp, Laurent Pradier, Konrad Beyreuther, Thomas A Bayer

Journal:

Neuroscience Letters

Year:

2001

Language:

english

File:

PDF, 581 KB

english, 2001

45

Reelin in plaques of β-amyloid precursor protein and presenilin-1 double-transgenic mice

Oliver Wirths, Gerd Multhaup, Christian Czech, Véronique Blanchard, Günter Tremp, Laurent Pradier, Konrad Beyreuther, Thomas A. Bayer

Journal:

Neuroscience Letters

Year:

2001

Language:

english

File:

PDF, 195 KB

english, 2001

46

Copper in disorders with neurological symptoms: Alzheimer’s, Menkes, and Wilson diseases

Daniel Strausak, Julian F.B Mercer, Hermann H Dieter, Wolfgang Stremmel, Gerd Multhaup

Journal:

Brain Research Bulletin

Year:

2001

Language:

english

File:

PDF, 306 KB

english, 2001

47

No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the β-cleaved C-terminal APP fragment

Bart P.F Rutten, Oliver Wirths, Wilma D.J Van de Berg, Stefan F Lichtenthaler, Jochen Vehoff, Harry W.M Steinbusch, Hubert Korr, Konrad Beyreuther, Gerd Multhaup, Thomas A Bayer, Christoph Schmitz

Journal:

Neurobiology of Disease

Year:

2003

Language:

english

File:

PDF, 608 KB

english, 2003

48

Toxicity of Alzheimer's disease-associated Aβ peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability

Hua, Haiqing, Münter, Lisa, Harmeier, Anja, Georgiev, Oleg, Multhaup, Gerd, Schaffner, Walter

Journal:

Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.89 MB

english, 2011

49

Cloning and expression of the 58 kd β subunit of the inhibitory glycine receptor

Gabriele Grenningloh, Iris Pribilla, Peter Prior, Gerd Multhaup, Konrad Beyreuther, Omar Taleb, Heinrich Betz

Journal:

Year:

1990

Language:

english

File:

PDF, 1.64 MB

english, 1990

50

Proteome of Metastatic Canine Mammary Carcinomas: Similarities to and Differences from Human Breast Cancer †

Klopfleisch, Robert, Klose, Patricia, Weise, Christoph, Bondzio, Angelika, Multhaup, Gerd, Einspanier, Ralf, Gruber, Achim D.

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 482 KB

english, 2010

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